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Mayo Clinic Health System in Lake City

651-345-3321 Appointments Locations

Perched on Lake Pepin, Mayo Clinic Health System in Lake City blends riverfront beauty with award-winning care, including hospital, clinic and long-term services recognized for excellence in stroke treatment.

VirtualCare

Virtual Care 24/7

Download our Primary Care On Demand app to access video visits with a Mayo Clinic provider from wherever you are in Minnesota, Iowa and Wisconsin. Available 24/7/365 for patients age 3 and older. You can address a wide range of common health concerns through virtual appointments, including cold and flu symptoms, rash, sinus pressure, diabetes, urinary tract pain, blood pressure issues and more.

Learn more about virtual care

Find Us

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Hospital and Clinic
  • Clinic Hours:
  • Mon-Fri:7:00 AM - 5:00 PM
  • Emergency Department Hours:
    Open 24 hours
Directions
500 W. Grant St., Lake City, MN 55041
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Care Center
  • Care Center Hours:
  • Open 24 hours
Directions
500 W. Grant St., Lake City, MN 55041
Recent blogs from Mayo Clinic Health System
Pink eye: Symptoms, causes and when to seek care
Pink eye is a common eye condition that affects people of all ages and can be uncomfortable and, in some cases, contagious.
April 6, 2026
When to seek care for cold, flu and RSV

If you are dealing with coughs, fevers or congestion, know when to seek medical care and when symptoms can be managed at home.

March 10, 2026
Is your sinus pressure a sinus infection?
Sinus infections (acute sinusitis) occur when the air‑filled spaces around your nose become inflamed and swollen.
February 9, 2026
Unexpected vacation ending leads to rare tumor discovery
After a family vacation, Izzy Iverson started having significant pain. Her family soon learned she would need surgery to remove a rare tumor in her chest called a teratoma.
February 5, 2026
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Mayo Clinic Health System in Lake City